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Alkyne terminated poly-L-lysine hydrochloride or Poly-L-lysine hydrochloride alkyne (PLL-Alkyne) is a positively charged synthetic
polyamino acid having one HCl per lysine unit and alkyne group on the N-terminal. It is a crystalline solid soluble in water.
Applications for poly-L-lysine hydrobromide include the promotion of cell adhesion to solid substrates for culture dishes or slides,
the conjugation to active molecules for improved activities, the layer-by-layer deposition techniques, and the complexation with
nucleic acids for gene expression.
Alkyne-terminated polymers were used to react azide group “click” chemistry in mild condition, which is very useful for