Acetal-Poly-L-lysine View larger


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Weight3300(X=20), 8,200 (X=50), 16,000 (X=100), 32,000 (X=200)

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Acetal-capped poly-L-lysine (Acetal-poly-L-Lysine, Acetal-PLL) is a positively charged synthetic polyamino acid. It is a crystalline
solid soluble in water. Applications for poly-L-lysine include the promotion of cell adhesion to solid substrates for culture dishes or
slides, the conjugation to active molecules for improved activities, the layer-by-layer deposition techniques, and the complexation
with nucleic acids for gene expression.
Acetal-functionalized polymers can be easily reduced to aldehyde group using acidic aqueous conditions (pH=2-4). Aldehyde
group can selectively react with amine or thiol group in aqueous solution.